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A lot, like A LOT, of medical research is poorly done on the statistical side. The main critique I would have of this study is that the study design doesn’t seem to speak to the research question of interest (what is the effect of GAM on mental health?), and so they’ve tried to come around to it in a hacky way and not done a great job.

It’s common in studies of adolescent development to consider a flat trajectory a big success if the trajectory of a comparison group is going down, so I’m less concerned on that point. A lot of things get worse in adolescence and then recover.

I’m more concerned on selective attrition. It is absolutely not common to have 40% of your sample drop out within a year in a longitudinal study. It’s really hard to conclude anything with that kind of drop out.

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I worked in a developmental biology lab in college and was kind of devastated to learn people aren’t really checking on each other like I had expected/been told since I was a kid.

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AI could be very well deployed to serve as a filter for where we need to dive deeper on papers. Serving as a comprehensive first level reviewer, given the sheer volume of published work out there.

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I’m not sure what you’d use as the training set there but am open to ideas. Peer review, as currently deployed, seems to be kinda shitty to be honest.

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Google's 540B language model that was announced this week is incredibly impressive (deciphering jokes, inference chains). Don't think it would be too much of a leap to train an AI to be able to read methodology sections to ascertain statistical method being used and whether it's questionable given the research question at hand. Training set would probably be a collection of widely-considered high quality papers along with a reference table of statistical methods to generally-appropriate applications.

Not saying it's readily doable now, but could be a good automated way to attempt and flag what obviously needs greater scrutiny.

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I am an article reviewer for several journals, I cant imagine a machine getting to my level

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It's not about getting to your level necessarily, it's about being able to deploy it across millions of pages of articles to quickly bucket / assess where there may be misapplied methodologies, etc. - FOR FURTHER INVESTIGTION BY EXPERIENCED REVIEWERS

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