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Interesting. Do those other made-up cultural phenomena you mentioned there, like windigo and susto, also have observable biological markers and correlations with prenatal hormone exposure? Or is that unique to the made-up cultural phenomenon known as "being trans"?

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I see you didn’t fully read the article then, so it’s impossible to engage fruitfully: what is underlying windigo? A real thing, anxiety. What is underlying “being trans” (as well as other cultures’ extremely varied expressions of similar phenomena?)? Gender nonconformity, a real thing, which may indeed across cultures and across times and places have underlying biological causes, be related to hormones etc.

What is unique and made up is not gender nonconformity (there are always, say, some extremely feminine men in each culture). What is made up is our wrong body narrative and set of “treatments” and beliefs which other cultures (including cultures with better outcomes for their GNC people) do not share.

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Homosexuality has biomarkers; gender dysphoria not so much. And yes, windigo would have indistinguishable biomarkers from generalized anxiety (e.g. elevated cortisol)

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Gender identity does indeed have biomarkers.

Women with CAIS are significantly more likely to report viewing themselves as a gender other than female, score especially low on assessments of female gender identity, and score especially high on assessments of male gender identity, independent of their sexual orientation. Contrast this to women with MRKHS, another intersex condition, who report (and are assessed with) a female gender identity at typical rates, despite having more atypical physical sexual development. [1]

Trans women show a female-typical pattern of activation in the hypothalamus when smelling steroids that are known to have a sex-linked effect on the hypothalamus, independent of sexual orientation. [2]

Trans women also show female-typical levels of gray matter volume in specific regions of the brain, independent of sexual orientation. [3]

[1] https://www.sciencedirect.com/science/article/abs/pii/S0191886909004620

[2] https://academic.oup.com/cercor/article/18/8/1900/285954

[3] https://www.sciencedirect.com/science/article/abs/pii/S1053811909003176

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